SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03207

Signal sequence   MLQFSLSPTLSMGFHVIAMVALLFSHVDHISA

Length  32

Organism  Bos taurus (Bovine)

UniProt ID  P48765,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03207.cif

Structure  SPKB03207.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3501.18014

Aliphatic index  121.875

Isoelectric point  6.792322458

Charge (pH=7)   -0.728841944

Topological polar surface area  1244.44

Aromaticity  0.09375

Average rotatable bonds  3.46875

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  47

X logP energy  -8.1176

Hydropathy 



Literature Information


Title  Purification and amino-terminal sequence of the bovine cardiac sodium-calcium exchanger: evidence for the presence of a signal sequence.

DOI  10.1016/0003-9861(91)90553-u,

Publication Year  1991

PubMed ID  1929404,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.