SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03204

Signal sequence   MNWLFLVSLVFFCGVSTHPALA

Length  22

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  P48439,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6C26,

Predicted Structure ID  SPKB03204.cif

Structure  SPKB03204.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2452.95764

Aliphatic index  119.5454545

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  813.88

Aromaticity  0.181818182

Average rotatable bonds  3.272727273

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -2.7495

Hydropathy 



Literature Information


Title  Functional characterization of Ost3p. Loss of the 34-kD subunit of the Saccharomyces cerevisiae oligosaccharyltransferase results in biased underglycosylation of acceptor substrates.

DOI  10.1083/jcb.130.3.567,

Publication Year  1995

PubMed ID  7622558,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.