SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03203

Signal sequence   MDPARPLGLSILLLFLTEAALG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P48307,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03203.cif

Structure  SPKB03203.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2311.80814

Aliphatic index  155.4545455

Isoelectric point  4.184407676

Charge (pH=7)   -0.999797405

Topological polar surface area  833.8

Aromaticity  0.045454545

Average rotatable bonds  3.318181818

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -3.74553

Hydropathy 



Literature Information


Title  Purification and characterization of placental protein 5.

DOI  10.1016/0006-291x(88)90546-3,

Publication Year  1988

PubMed ID  3276312,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.