SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03201

Signal sequence   MRLLILTCLVAVALA

Length  15

Organism  Homo sapiens (Human)

UniProt ID  P47710,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03201.cif

Structure  SPKB03201.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1600.09724

Aliphatic index  214.6666667

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  552.85

Aromaticity  0

Average rotatable bonds  3.466666667

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  20

X logP energy  -0.83923

Hydropathy 



Literature Information


Title  Human alpha s1-casein: purification and characterization.

DOI  10.1016/0305-0491(94)00225-j,

Publication Year  1995

PubMed ID  7749638,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.