SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03197

Signal sequence   MKKTAIALVVAGLAAASVAQA

Length  21

Organism  Haemophilus influenzae

UniProt ID  P45996,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03197.cif

Structure  SPKB03197.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1984.42834

Aliphatic index  135.2380952

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  780.91

Aromaticity  0

Average rotatable bonds  3.142857143

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -7.3591

Hydropathy 



Literature Information


Title  Role of fimbriae expressed by nontypeable Haemophilus influenzae in pathogenesis of and protection against otitis media and relatedness of the fimbrin subunit to outer membrane protein A.

DOI  10.1128/iai.62.5.2002-2020.1994,

Publication Year  1994

PubMed ID  7909539,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.