SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03196

Signal sequence   MRTLWIMAVLLVGVEG

Length  16

Organism  Bothrops jararacussu (Jararacussu)

UniProt ID  P45881,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03196.cif

Structure  SPKB03196.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1788.23974

Aliphatic index  158.125

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  635.04

Aromaticity  0.0625

Average rotatable bonds  3.625

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  -1.15553

Hydropathy 



Literature Information


Title  The amino acid sequence of bothropstoxin-II, an Asp-49 myotoxin from Bothrops jararacussu (Jararacucu) venom with low phospholipase A2 activity.

DOI  10.1023/a:1022563401413,

Publication Year  1998

PubMed ID  9619591,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.