SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03194

Signal sequence   MNYLVMISFALLLMTGVES

Length  19

Organism  Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)

UniProt ID  P45697,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03194.cif

Structure  SPKB03194.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2132.61934

Aliphatic index  138.4210526

Isoelectric point  3.849982713

Charge (pH=7)   -1.001090992

Topological polar surface area  748.43

Aromaticity  0.105263158

Average rotatable bonds  3.684210526

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  29

X logP energy  -3.1256

Hydropathy 



Literature Information


Title  Two neurotoxins (BmK I and BmK II) from the venom of the scorpion Buthus martensi Karsch: purification, amino acid sequences and assessment of specific activity.

DOI  10.1016/0041-0101(96)00065-7,

Publication Year  1996

PubMed ID  8896191,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.