SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03193

Signal sequence   MNYLIMFSLALLLVIGVES

Length  19

Organism  Androctonus australis (Sahara scorpion)

UniProt ID  P45658,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03193.cif

Structure  SPKB03193.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2126.64044

Aliphatic index  179.4736842

Isoelectric point  3.849982713

Charge (pH=7)   -1.001090992

Topological polar surface area  728.2

Aromaticity  0.105263158

Average rotatable bonds  3.684210526

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -1.1673

Hydropathy 



Literature Information


Title  The amino acid sequence of toxin IV from the Androctonus australis scorpion: differing effects of natural mutations in scorpion alpha-toxins on their antigenic and toxic properties.

DOI  10.1002/nt.2620010112,

Publication Year  1992

PubMed ID  1344902,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.