SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03189

Signal sequence   MHPGVLAAFLFLSWTHCRA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P45452,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03189.cif

Structure  SPKB03189.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2157.58184

Aliphatic index  92.63157895

Isoelectric point  8.564795175

Charge (pH=7)   1.117824454

Topological polar surface area  753.84

Aromaticity  0.157894737

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  27

X logP energy  -3.42343

Hydropathy 



Literature Information


Title  Biochemical characterization of human collagenase-3.

DOI  10.1074/jbc.271.3.1544,

Publication Year  1996

PubMed ID  8576151,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.