SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03187

Signal sequence   MSLLVVSMACVGFFLLQGAWP

Length  21

Organism  Homo sapiens (Human)

UniProt ID  P43626,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03187.cif

Structure  SPKB03187.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2269.80624

Aliphatic index  125.2380952

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  735.87

Aromaticity  0.142857143

Average rotatable bonds  3.285714286

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -2.049

Hydropathy 



Literature Information


Title  Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

DOI  10.1016/1074-7613(95)90025-x,

Publication Year  1995

PubMed ID  7749980,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.