SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03186

Signal sequence   MMMLITMKSTVLLSVFTVLATWAGLLEA

Length  28

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  P43555,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03186.cif

Structure  SPKB03186.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3071.84374

Aliphatic index  139.2857143

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  1049.51

Aromaticity  0.071428571

Average rotatable bonds  3.607142857

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  41

X logP energy  -4.0496

Hydropathy 



Literature Information


Title  Partial purification and characterization of early and late endosomes from yeast. Identification of four novel proteins.

DOI  NA,

Publication Year  1993

PubMed ID  8314797,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.