General Information
SPKB ID SPKB03183
Signal sequence MRLLPRLLLLLLLVFPAT
Length 18
Organism Homo sapiens (Human)
UniProt ID P43307,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03183.cif
Physicochemical Information
Molecular weight 2092.74394
Aliphatic index 216.6666667
Isoelectric point 12.50010931
Charge (pH=7) 1.997977677
Topological polar surface area 684.47
Aromaticity 0.055555556
Average rotatable bonds 3.666666667
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 23
X logP energy 1.64624
Hydropathy
Literature Information
Title HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides.
DOI 10.1038/356443a0,
Publication Year 1992
PubMed ID 1557127,
Patent ID NA,