SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03182

Signal sequence   MGLPRLVCAFLLAACCCCPRVAG

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P43121,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03182.cif

Structure  SPKB03182.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2368.00864

Aliphatic index  110.4347826

Isoelectric point  8.215052028

Charge (pH=7)   1.688104097

Topological polar surface area  809.74

Aromaticity  0.043478261

Average rotatable bonds  3.086956522

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -5.91356

Hydropathy 



Literature Information


Title  Isolation and functional characterization of the A32 melanoma-associated antigen.

DOI  NA,

Publication Year  1994

PubMed ID  8162602,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.