General Information
SPKB ID SPKB03181
Signal sequence MSLLSSRAARVPGPSSSLCALLVLLLLLTQPGPIAS
Length 36
Organism Homo sapiens (Human)
UniProt ID P42830,
Motif 1..36
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03181.cif
Physicochemical Information
Molecular weight 3633.40924
Aliphatic index 146.3888889
Isoelectric point 10.52640717
Charge (pH=7) 1.936002961
Topological polar surface area 1375.39
Aromaticity 0
Average rotatable bonds 3.166666667
Number of hydrogen bond donors 49
Number of hydrogen bond acceptors 50
X logP energy -13.64556
Hydropathy
Literature Information
Title Isolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoforms.
DOI 10.1046/j.1432-1327.1999.00166.x,
Publication Year 1999
PubMed ID 10095777,
Patent ID NA,