SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03178

Signal sequence   MTAPWRRLRSLVWEYWAGFLVCAFWIPDSRG

Length  31

Organism  Rattus norvegicus (Rat)

UniProt ID  P42264,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03178.cif

Structure  SPKB03178.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3771.42064

Aliphatic index  78.70967742

Isoelectric point  9.497464244

Charge (pH=7)   1.937367531

Topological polar surface area  1385.02

Aromaticity  0.225806452

Average rotatable bonds  3.580645161

Number of hydrogen bond donors  53

Number of hydrogen bond acceptors  44

X logP energy  -5.45582

Hydropathy 



Literature Information


Title  Crystal structures of the glutamate receptor ion channel GluK3 and GluK5 amino-terminal domains.

DOI  10.1016/j.jmb.2010.10.006,

Publication Year  2010

PubMed ID  20951142,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.