General Information
SPKB ID SPKB03176
Signal sequence MRQVWFSWIVGLFLCFFNVSSA
Length 22
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
UniProt ID P41543,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6C26,
Predicted Structure ID SPKB03176.cif
Physicochemical Information
Molecular weight 2638.14274
Aliphatic index 97.27272727
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 914.77
Aromaticity 0.272727273
Average rotatable bonds 3.636363636
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 31
X logP energy -3.18053
Hydropathy
Literature Information
Title The alpha subunit of the Saccharomyces cerevisiae oligosaccharyltransferase complex is essential for vegetative growth of yeast and is homologous to mammalian ribophorin I.
Publication Year 1995
PubMed ID 7860628,
Patent ID NA,