SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03175

Signal sequence   MISNGIGTVTAGKRSICLLPLLLIGLWGCVTC

Length  32

Organism  Bos taurus (Bovine)

UniProt ID  P41361,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03175.cif

Structure  SPKB03175.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3304.08874

Aliphatic index  143.125

Isoelectric point  8.522631274

Charge (pH=7)   1.811761806

Topological polar surface area  1204.58

Aromaticity  0.03125

Average rotatable bonds  3.34375

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  45

X logP energy  -9.45563

Hydropathy 



Literature Information


Title  The complete amino acid sequence of bovine antithrombin (ATIII).

DOI  10.1007/BF01024785,

Publication Year  1991

PubMed ID  1930634,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.