SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03172

Signal sequence   MDLVLKRCLLHLAVIGALLAVGAT

Length  24

Organism  Homo sapiens (Human)

UniProt ID  P40967,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03172.cif

Structure  SPKB03172.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2491.13504

Aliphatic index  182.9166667

Isoelectric point  8.552678977

Charge (pH=7)   1.027066813

Topological polar surface area  906.75

Aromaticity  0

Average rotatable bonds  3.458333333

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -3.87563

Hydropathy 



Literature Information


Title  Cloning and expression of the gene for the melanoma-associated ME20 antigen.

DOI  10.1089/dna.1994.13.87,

Publication Year  1994

PubMed ID  8179825,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.