SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03171

Signal sequence   MMFNKQIFTILILSLSLALAGSGCISEGAEDNVA

Length  34

Organism  Methanosarcina thermophila (strain ATCC 43570 / DSM 1825 / OCM 12 / VKM B-1830 / TM-1)

UniProt ID  P40881,

Motif  1..34



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1QQ0,

Predicted Structure ID  SPKB03171.cif

Structure  SPKB03171.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3558.18044

Aliphatic index  123.5294118

Isoelectric point  3.927538349

Charge (pH=7)   -2.060288721

Topological polar surface area  1391.96

Aromaticity  0.058823529

Average rotatable bonds  3.558823529

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  50

X logP energy  -12.9376

Hydropathy 



Literature Information


Title  A carbonic anhydrase from the archaeon Methanosarcina thermophila.

DOI  10.1073/pnas.91.15.6909,

Publication Year  1994

PubMed ID  8041719,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.