SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03170

Signal sequence   MARLALSPVPSHWMVALLLLLSAEPVPA

Length  28

Organism  Homo sapiens (Human)

UniProt ID  P40259,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7XQ8,

Predicted Structure ID  SPKB03170.cif

Structure  SPKB03170.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2983.66674

Aliphatic index  146.4285714

Isoelectric point  7.551312718

Charge (pH=7)   0.090665202

Topological polar surface area  1018.22

Aromaticity  0.035714286

Average rotatable bonds  3.142857143

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  37

X logP energy  -3.79613

Hydropathy 



Literature Information


Title  Isolation and chemical characterization of the human B29 and mb-1 proteins of the B cell antigen receptor complex.

DOI  10.1016/0161-5890(94)90061-2,

Publication Year  1994

PubMed ID  7514267,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.