SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03164

Signal sequence   MKRHLNTCYRLVWNHMTGAFVVASELARARGKRGGVAVALSLAAVTSLPVLA

Length  52

Organism  Escherichia coli (strain K12)

UniProt ID  P39180,

Motif  1..52



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03164.cif

Structure  SPKB03164.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5564.62344

Aliphatic index  108.8461538

Isoelectric point  11.97059154

Charge (pH=7)   6.11814585

Topological polar surface area  2238.41

Aromaticity  0.057692308

Average rotatable bonds  3.480769231

Number of hydrogen bond donors  83

Number of hydrogen bond acceptors  75

X logP energy  -21.15945

Hydropathy 



Literature Information


Title  Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.

DOI  10.1002/elps.1150180807,

Publication Year  1997

PubMed ID  9298646,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.