SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03162

Signal sequence   MLHKKTLLFAALSAALWGGATQAADA

Length  26

Organism  Escherichia coli (strain K12)

UniProt ID  P39172,

Motif  1..26



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  2OGW,

Predicted Structure ID  SPKB03162.cif

Structure  SPKB03162.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2657.12584

Aliphatic index  105.7692308

Isoelectric point  9.539371756

Charge (pH=7)   1.088749807

Topological polar surface area  1028.41

Aromaticity  0.076923077

Average rotatable bonds  3.307692308

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  36

X logP energy  -8.3915

Hydropathy 



Literature Information


Title  Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.

DOI  10.1002/elps.1150180807,

Publication Year  1997

PubMed ID  9298646,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.