SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03160

Signal sequence   MKKQTQLLSALALSVGLTLSASFQAVA

Length  27

Organism  Escherichia coli (strain K12)

UniProt ID  P39099,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8KIC,

Predicted Structure ID  SPKB03160.cif

Structure  SPKB03160.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2777.31524

Aliphatic index  126.6666667

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  1122.61

Aromaticity  0.037037037

Average rotatable bonds  3.518518519

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  40

X logP energy  -11.8963

Hydropathy 



Literature Information


Title  Characterization of degQ and degS, Escherichia coli genes encoding homologs of the DegP protease.

DOI  10.1128/jb.178.4.1146-1153.1996,

Publication Year  1996

PubMed ID  8576051,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.