SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03159

Signal sequence   MKQSSPEPLRPRRTGGRGGARRAAALVTIPLLPMTLLGASPALADASGA

Length  49

Organism  Actinomadura sp. (strain R39)

UniProt ID  P39045,

Motif  1..49



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03159.cif

Structure  SPKB03159.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4938.79104

Aliphatic index  87.95918367

Isoelectric point  12.50562841

Charge (pH=7)   4.999891005

Topological polar surface area  2064.1

Aromaticity  0

Average rotatable bonds  3.204081633

Number of hydrogen bond donors  73

Number of hydrogen bond acceptors  69

X logP energy  -25.37038

Hydropathy 



Literature Information


Title  Primary and predicted secondary structures of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.

DOI  10.1042/bj2820781,

Publication Year  1992

PubMed ID  1554361,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.