General Information
SPKB ID SPKB03155
Signal sequence MKMRFLGLVVCLVLWTLHSEGSGGKLT
Length 27
Organism Homo sapiens (Human)
UniProt ID P38571,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03155.cif
Physicochemical Information
Molecular weight 2976.64974
Aliphatic index 118.8888889
Isoelectric point 9.674863725
Charge (pH=7) 2.028100418
Topological polar surface area 1096.55
Aromaticity 0.074074074
Average rotatable bonds 3.703703704
Number of hydrogen bond donors 41
Number of hydrogen bond acceptors 40
X logP energy -6.72593
Hydropathy 
Literature Information
Title Purification, characterization and molecular cloning of human hepatic lysosomal acid lipase.
DOI 10.1111/j.1432-1033.1994.tb18572.x,
Publication Year 1994
PubMed ID 8112342,
Patent ID NA,
