SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03154

Signal sequence   MWLFHTLLCIASLALLAA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P38570,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03154.cif

Structure  SPKB03154.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1987.49184

Aliphatic index  173.8888889

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  642.95

Aromaticity  0.111111111

Average rotatable bonds  3.388888889

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  24

X logP energy  0.0307

Hydropathy 



Literature Information


Title  Molecular cloning of the human mucosal lymphocyte integrin alpha E subunit. Unusual structure and restricted RNA distribution.

DOI  NA,

Publication Year  1994

PubMed ID  8119947,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.