SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03151

Signal sequence   MLLQESAGVWLALALVTALTPSPSMA

Length  26

Organism  Mus musculus (Mouse)

UniProt ID  P37889,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03151.cif

Structure  SPKB03151.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2671.20554

Aliphatic index  131.5384615

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  970.57

Aromaticity  0.038461538

Average rotatable bonds  3.153846154

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  36

X logP energy  -7.0508

Hydropathy 



Literature Information


Title  Structure and expression of fibulin-2, a novel extracellular matrix protein with multiple EGF-like repeats and consensus motifs for calcium binding.

DOI  10.1083/jcb.123.5.1269,

Publication Year  1993

PubMed ID  8245130,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.