SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03147

Signal sequence   MAKSLFRALVALSFLAPLWLNA

Length  22

Organism  Escherichia coli (strain K12)

UniProt ID  P37028,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03147.cif

Structure  SPKB03147.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2432.99574

Aliphatic index  142.2727273

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  852.89

Aromaticity  0.136363636

Average rotatable bonds  3.454545455

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -2.66783

Hydropathy 



Literature Information


Title  Identification of the periplasmic cobalamin-binding protein BtuF of Escherichia coli.

DOI  10.1128/JB.184.3.706-717.2002,

Publication Year  2002

PubMed ID  11790740,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.