SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03146

Signal sequence   MWLLVSVILISRISSVGG

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P36980,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03146.cif

Structure  SPKB03146.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1930.37934

Aliphatic index  178.3333333

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  716.63

Aromaticity  0.055555556

Average rotatable bonds  3.5

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  25

X logP energy  -4.14313

Hydropathy 



Literature Information


Title  Two additional human serum proteins structurally related to complement factor H. Evidence for a family of factor H-related genes.

DOI  NA,

Publication Year  1992

PubMed ID  1533657,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.