SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03145

Signal sequence   MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATA

Length  33

Organism  Homo sapiens (Human)

UniProt ID  P36897,

Motif  1..33



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03145.cif

Structure  SPKB03145.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3096.76844

Aliphatic index  145.7575758

Isoelectric point  10.39777148

Charge (pH=7)   0.9997528

Topological polar surface area  1149.48

Aromaticity  0

Average rotatable bonds  2.818181818

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  39

X logP energy  -8.47966

Hydropathy 



Literature Information


Title  Type I transforming growth factor beta receptor maps to 9q22 and exhibits a polymorphism and a rare variant within a polyalanine tract.

DOI  NA,

Publication Year  1998

PubMed ID  9661882,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.