SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03144

Signal sequence   MAQRIFTLILLLCSTSVFA

Length  19

Organism  Escherichia coli (strain K12)

UniProt ID  P36655,

Motif  1..19



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03144.cif

Structure  SPKB03144.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2127.63124

Aliphatic index  148.9473684

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  773.03

Aromaticity  0.105263158

Average rotatable bonds  3.631578947

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  28

X logP energy  -4.45963

Hydropathy 



Literature Information


Title  Transfer of electrons across the cytoplasmic membrane by DsbD, a membrane protein involved in thiol-disulphide exchange and protein folding in the bacterial periplasm.

DOI  10.1046/j.1365-2958.2000.01778.x,

Publication Year  2000

PubMed ID  10712691,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.