General Information
SPKB ID SPKB03140
Signal sequence MGVKASQTGFVVLVLLQCCSA
Length 21
Organism Homo sapiens (Human)
UniProt ID P36222,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8R41,
Predicted Structure ID SPKB03140.cif
Physicochemical Information
Molecular weight 2154.62904
Aliphatic index 120.4761905
Isoelectric point 8.229691165
Charge (pH=7) 0.873739834
Topological polar surface area 818.21
Aromaticity 0.047619048
Average rotatable bonds 3.380952381
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 31
X logP energy -7.96
Hydropathy
Literature Information
Title Human synovial cells secrete a 39 kDa protein similar to a bovine mammary protein expressed during the non-lactating period.
DOI 10.1042/bj2690265,
Publication Year 1990
PubMed ID 2375755,
Patent ID NA,