SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03138

Signal sequence   MALRTGGPALVVLLAFWVALGPC

Length  23

Organism  Rattus norvegicus (Rat)

UniProt ID  P35859,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03138.cif

Structure  SPKB03138.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2355.92814

Aliphatic index  140

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  783.86

Aromaticity  0.086956522

Average rotatable bonds  3

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -2.45773

Hydropathy 



Literature Information


Title  Purification and characterization of the acid-labile subunit of rat serum insulin-like growth factor binding protein complex.

DOI  10.1210/endo.134.2.7507839,

Publication Year  1994

PubMed ID  7507839,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.