General Information
SPKB ID SPKB03136
Signal sequence MTPWLGLIVLLGSWSLGDWGAEA
Length 23
Organism Homo sapiens (Human)
UniProt ID P35625,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03136.cif
Physicochemical Information
Molecular weight 2472.88394
Aliphatic index 123.0434783
Isoelectric point 3.550073557
Charge (pH=7) -1.999794094
Topological polar surface area 877.39
Aromaticity 0.130434783
Average rotatable bonds 3.217391304
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 30
X logP energy -3.3019
Hydropathy 
Literature Information
Title Identification and characterization of human tissue inhibitor of metalloproteinase-3 and detection of three additional metalloproteinase inhibitor activities in extracellular matrix.
DOI 10.1016/0945-053x(95)90005-5,
Publication Year 1995
PubMed ID 7795886,
Patent ID NA,
