General Information
SPKB ID SPKB03134
Signal sequence MRRGRLLEIALGFTVLLASYTSHG
Length 24
Organism Homo sapiens (Human)
UniProt ID P35555,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03134.cif
Physicochemical Information
Molecular weight 2662.14844
Aliphatic index 117.9166667
Isoelectric point 11.05370107
Charge (pH=7) 2.089808165
Topological polar surface area 1085.45
Aromaticity 0.083333333
Average rotatable bonds 3.666666667
Number of hydrogen bond donors 41
Number of hydrogen bond acceptors 36
X logP energy -9.27399
Hydropathy
Literature Information
Title Initial steps in assembly of microfibrils. Formation of disulfide-cross-linked multimers containing fibrillin-1.
Publication Year 2000
PubMed ID 10636927,
Patent ID NA,