SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03131

Signal sequence   MELLRGLGVLFLLHMCGS

Length  18

Organism  Mus musculus (Mouse)

UniProt ID  P35441,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03131.cif

Structure  SPKB03131.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1989.48284

Aliphatic index  146.1111111

Isoelectric point  7.360093818

Charge (pH=7)   0.028690486

Topological polar surface area  706.13

Aromaticity  0.055555556

Average rotatable bonds  3.722222222

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -2.76843

Hydropathy 



Literature Information


Title  Expression and initial characterization of recombinant mouse thrombospondin 1 and thrombospondin 3.

DOI  10.1016/0014-5793(96)00460-7,

Publication Year  1996

PubMed ID  8654563,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.