SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03130

Signal sequence   MLFRAVLLCAALALSHA

Length  17

Organism  Rattus norvegicus (Rat)

UniProt ID  P35355,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03130.cif

Structure  SPKB03130.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1800.25364

Aliphatic index  161.1764706

Isoelectric point  8.557478416

Charge (pH=7)   1.026915363

Topological polar surface area  639.73

Aromaticity  0.058823529

Average rotatable bonds  3.352941176

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  -2.71193

Hydropathy 



Literature Information


Title  Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide synthase induced by human chorionic gonadotropin in granulosa cells of rat preovulatory follicles.

DOI  NA,

Publication Year  1992

PubMed ID  1556140,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.