SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03128

Signal sequence   MKTTCFLISLILIQGTKN

Length  18

Organism  Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980))

UniProt ID  P35253,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03128.cif

Structure  SPKB03128.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2024.50774

Aliphatic index  130

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  777.16

Aromaticity  0.055555556

Average rotatable bonds  3.888888889

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -5.9929

Hydropathy 



Literature Information


Title  Marburg virus gene 4 encodes the virion membrane protein, a type I transmembrane glycoprotein.

DOI  10.1128/JVI.67.3.1203-1210.1993,

Publication Year  1993

PubMed ID  8437211,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.