SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03127

Signal sequence   MLHFLSMLVLLVQPLGDLG

Length  19

Organism  Rattus norvegicus (Rat)

UniProt ID  P35248,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03127.cif

Structure  SPKB03127.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2096.61714

Aliphatic index  174.2105263

Isoelectric point  5.292257586

Charge (pH=7)   -0.910660126

Topological polar surface area  707.63

Aromaticity  0.052631579

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  26

X logP energy  -1.0244

Hydropathy 



Literature Information


Title  Primary structure of rat pulmonary surfactant protein D. cDNA and deduced amino acid sequence.

DOI  NA,

Publication Year  1992

PubMed ID  1370483,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.