General Information
SPKB ID SPKB03126
Signal sequence MELRARGWWLLCAAAALVACTRG
Length 23
Organism Rattus norvegicus (Rat)
UniProt ID P35053,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03126.cif
Physicochemical Information
Molecular weight 2519.04174
Aliphatic index 106.5217391
Isoelectric point 8.834786621
Charge (pH=7) 1.875800056
Topological polar surface area 978.33
Aromaticity 0.086956522
Average rotatable bonds 3.434782609
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 32
X logP energy -6.61739
Hydropathy
Literature Information
Title Cloning of a major heparan sulfate proteoglycan from brain and identification as the rat form of glypican.
DOI 10.1016/0006-291x(92)92398-h,
Publication Year 1992
PubMed ID 1417860,
Patent ID NA,