General Information
SPKB ID SPKB03124
Signal sequence MGGHPQLRLVKALLLLGLNPVSA
Length 23
Organism Homo sapiens (Human)
UniProt ID P34998,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03124.cif
Physicochemical Information
Molecular weight 2397.95094
Aliphatic index 152.6086957
Isoelectric point 11.65178972
Charge (pH=7) 2.088595045
Topological polar surface area 908.95
Aromaticity 0
Average rotatable bonds 3.391304348
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 31
X logP energy -6.11063
Hydropathy
Literature Information
Title Expression, purification, and characterization of a soluble form of the first extracellular domain of the human type 1 corticotropin releasing factor receptor.
Publication Year 2001
PubMed ID 11425856,
Patent ID NA,