SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03120

Signal sequence   MKIILILSIFLICFLQLGQS

Length  20

Organism  Dictyostelium discoideum (Social amoeba)

UniProt ID  P34115,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03120.cif

Structure  SPKB03120.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2293.93764

Aliphatic index  195

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  768.88

Aromaticity  0.1

Average rotatable bonds  3.95

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -0.4852

Hydropathy 



Literature Information


Title  Molecular cloning and characterization of two genes encoding gp138, a cell surface glycoprotein involved in the sexual cell fusion of Dictyostelium discoideum.

DOI  10.1006/dbio.1993.1070,

Publication Year  1993

PubMed ID  7680629,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.