General Information
SPKB ID SPKB03119
Signal sequence MALQRTHSLLLLLLLTLLGLGLVQPSYG
Length 28
Organism Homo sapiens (Human)
UniProt ID P34096,
Motif 1..28
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03119.cif
Physicochemical Information
Molecular weight 3034.73704
Aliphatic index 181.0714286
Isoelectric point 9.351184298
Charge (pH=7) 1.088039665
Topological polar surface area 1118.14
Aromaticity 0.035714286
Average rotatable bonds 3.571428571
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 39
X logP energy -5.67493
Hydropathy
Literature Information
Title The amino acid sequence of human ribonuclease 4, a highly conserved ribonuclease that cleaves specifically on the 3' side of uridine.
DOI 10.1111/j.1432-1033.1993.tb18259.x,
Publication Year 1993
PubMed ID 8223579,
Patent ID NA,