General Information
SPKB ID SPKB03118
Signal sequence MKAIVFVLIFAVAFAVTATHQ
Length 21
Organism Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
UniProt ID P34095,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03118.cif
Physicochemical Information
Molecular weight 2277.79634
Aliphatic index 134.7619048
Isoelectric point 9.702001779
Charge (pH=7) 1.088598356
Topological polar surface area 783.57
Aromaticity 0.142857143
Average rotatable bonds 3.380952381
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 28
X logP energy -2.4408
Hydropathy 
Literature Information
Title Primary and secondary structure of the pore-forming peptide of pathogenic Entamoeba histolytica.
DOI 10.1002/j.1460-2075.1992.tb05432.x,
Publication Year 1992
PubMed ID 1396552,
Patent ID NA,
