SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03115

Signal sequence   MRTDWNFFFCILLQAIFVVG

Length  20

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  P33767,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6C26,

Predicted Structure ID  SPKB03115.cif

Structure  SPKB03115.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2420.91544

Aliphatic index  112

Isoelectric point  6.161167719

Charge (pH=7)   -0.063547244

Topological polar surface area  837.62

Aromaticity  0.25

Average rotatable bonds  3.75

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  28

X logP energy  -1.60543

Hydropathy 



Literature Information


Title  An essential 45 kDa yeast transmembrane protein reacts with anti-nuclear pore antibodies: purification of the protein, immunolocalization and cloning of the gene.

DOI  NA,

Publication Year  1991

PubMed ID  1724755,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.