SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03111

Signal sequence   MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATA

Length  39

Organism  Escherichia coli (strain K12)

UniProt ID  P33225,

Motif  1..39



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  9H4T,

Predicted Structure ID  SPKB03111.cif

Structure  SPKB03111.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4215.90764

Aliphatic index  90.25641026

Isoelectric point  12.67612163

Charge (pH=7)   3.998414227

Topological polar surface area  1814.94

Aromaticity  0.051282051

Average rotatable bonds  3.564102564

Number of hydrogen bond donors  64

Number of hydrogen bond acceptors  58

X logP energy  -21.49625

Hydropathy 



Literature Information


Title  TMAO anaerobic respiration in Escherichia coli: involvement of the tor operon.

DOI  10.1111/j.1365-2958.1994.tb00393.x,

Publication Year  1994

PubMed ID  8022286,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.