SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03109

Signal sequence   MRVVAAAMLYFYIVVLAICSVGIQG

Length  25

Organism  Sambucus nigra (European elder)

UniProt ID  P33183,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03109.cif

Structure  SPKB03109.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2688.34324

Aliphatic index  152

Isoelectric point  8.506546087

Charge (pH=7)   0.934305444

Topological polar surface area  927.4

Aromaticity  0.12

Average rotatable bonds  3.4

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  34

X logP energy  -3.01723

Hydropathy 



Literature Information


Title  Isolation and partial characterization of nigrin b, a non-toxic novel type 2 ribosome-inactivating protein from the bark of Sambucus nigra L.

DOI  10.1007/BF00028990,

Publication Year  1993

PubMed ID  8400135,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.