SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03108

Signal sequence   MALTFYLLVALVVLSYKSFSSLG

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P32881,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03108.cif

Structure  SPKB03108.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2523.06874

Aliphatic index  148.2608696

Isoelectric point  9.145600227

Charge (pH=7)   0.995988437

Topological polar surface area  871.15

Aromaticity  0.173913043

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -3.4062

Hydropathy 



Literature Information


Title  Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes.

DOI  10.1042/bj3290295,

Publication Year  1998

PubMed ID  9425112,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.