SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03101

Signal sequence   MMFNIYLFVTFFSTILA

Length  17

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  P32472,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03101.cif

Structure  SPKB03101.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2058.52404

Aliphatic index  114.7058824

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  652.93

Aromaticity  0.294117647

Average rotatable bonds  3.705882353

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  0.07

Hydropathy 



Literature Information


Title  Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2.

DOI  10.1073/pnas.89.16.7471,

Publication Year  1992

PubMed ID  1380159,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.