SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03095

Signal sequence   MAYYNTLALLTIFIFSGAFHRAQG

Length  24

Organism  Aquarana catesbeiana (American bullfrog) (Rana catesbeiana)

UniProt ID  P31779,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03095.cif

Structure  SPKB03095.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2706.15714

Aliphatic index  97.91666667

Isoelectric point  9.174205036

Charge (pH=7)   1.087189251

Topological polar surface area  1010.53

Aromaticity  0.208333333

Average rotatable bonds  3.5

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  35

X logP energy  -6.37673

Hydropathy 



Literature Information


Title  Purification and characterization of a 3,5,3'-L-triiodothyronine-specific binding protein from bullfrog tadpole plasma: a homolog of mammalian transthyretin.

DOI  10.1210/endo.132.5.8477670,

Publication Year  1993

PubMed ID  8477670,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.